FORTHCOMING

HUMAN CYTOGENETICS

M.K. BHASIN (University of Delhi, Delhi, India)

Pages: 500 + Figures • Size: 180 × 240 mm • Binding: Hard

It is difficult to ascertain who first studied human chromosomes. A number of researchers are credited with this honour (Arnold, 1879; von Winiwaster, 1912; Wieman, 1912; Painter, 1921; Hsu, 1952; Mittwoch, 1952; Darlington and Haque, 1955). However it was not until 1956, when Tjio and Levan established that human somatic cells have 46 chromosomes. The technical advances in human cytogenetics offer refinements in diagnosis. This is particularly important in genetic counselling and the investigation of foetal wastage. The use of cytogenetic techniques will expand particularly in the field of monitoring patients being treated with mutagenic drugs and the investigation of occupational and environmental hazards.

 CONTENTS

Preface

01. Introduction

02. Cell and Cell Division (Mitosis and Meiosis)
 

03. Human Chromosome and the Karyotype
 

04. Methods in Human Cytogenetics
 

05. Interphase Nucleus-X-and Y-Chromatin
 

06. DNA and Cell Chemistry
 

07. Chromosomal Abnormalities
 

08. Autosomal Chromosome Abnormalities
 

09. Sex Chromosome Abnormalities
 

10. Chromosome Abnormalities in Abortion

11. Chromosome and Cancer; Diseases Associated with Spontaneous Chromosome  

      Aberrations; Radiation, Viruses and Chemical Clastogens
 

12. Human Population Cytogenetics
 

13. Chromosomal Associations
 

14. Mapping of Human Chromosomes
 

15. Genetics and Mankind
 

16. Dermatoglyphics
 

     • Appendix
 

    • Glossary
 

     • Bibliography
 

    • Index

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