Inherited Disorders of Blood

Geeta Talukder (Vivekananda Institute of Medical Sciences, Kolkata, India) and Archana Sharma

2002•  Pages: 76. Size: 180x240•  Binding: Hard•  Price: US $ 35/-Rs. 850/-

(Special Issue of International Journal of Human Genetics - No. 1)

Inherited disorders of blood have been among the first diseases in man in which Mendelian Inheritance had been established . Bleeding diseases like haemophilias had been discussed in ancient  texts and known to be passed from mother to son. With the improved molecular methods of analysis it has now been established that haemoglobinopathies including thalassaemias are the commonest single gene disorders known in man.Red cells have been found to have many inherent defects, both of structure and function. Red cell enzyme defects like G6PD deficiency is also the commonest X linked  disorder in man. Structural red cell defects like spherocytosis, elliptocytosis, acanthocytosis are inherited disorders which may cause anaemias. In the present special issue of Inherited Disorders of Blood, some topics are being discussed by experts in different subjects of the field. It is hoped that it will open up new  fields of research in human genetics.

CONTENTS

Editorial 

Swapan Kumar Das and Geeta Talukder • Beta Globin Gene and Related Diseases:  A Review.

Silviene F. Oliveira, Maria Angélica F. Pedrosa, Sandra M. B. Sousa,  Regina C. Mingroni-Netto, Kiyoko Abe-Sandes, Íris Ferrari,  Ana A. L. Barbosa, Maria Teresa B. M. Auricchio, and Maria de Nazaré Klautau-Guimarães • Heterogeneous distribution of HbS and HbC alleles in  Afro-derived Brazilian populations

S. L. Kate and D. P. Lingojwar • Epidemiology of Sickle Cell Disorder in the state of Maharashtra

Bani Sengupta, Madhusnata De, Indrajit Dasgupta, Sandeep Poddar, Shila Chakrabarti, Geeta Talukder, Ritushree Kukreti and Samir Brahmachari • Comparative study of haemoglobinopathies in tribal population of Arunachal Pradesh and Tripura (North East India)

Bani Gajra, Shila Chakraborti and Bani Sengupta • Prenatal Diagnosis of Thalassaemias

Neelam Varma • Constitutional Hypoplastic Anemia.

M. Ravi, Solomon F. D. Paul, and P. Venkatachalam • A Humoral Immune Index of Clinically Normal Human Subject

Arup Ratan Bandyopadhyay and Jayita (Ghoshal) Roy • A Study on the Role of Haptoglobin in Haemolytic Disease of the Newborn

Dilip K. Bhattacharya.• Functional Status of Platelets and Hereditary Platelet

disorders

Sivajee Sengupta • Bernard-Soulier Syndrome: An Inherited Platelet Disorder

Ajanta Halder, Debasis Bandyopadhyay,  Madhusnata De  and  Manisha De • Detection of Dna Damage Measured by Comet Assay in Pre and Post Chemotherapeutic Acute Lymphoblastic Leukaemia